Blar i forfatter "Jansen, Kirsten"

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    • Dietary calanus oil recovers metabolic flexibility and rescues postischemic cardiac function in obese female mice 

      Jansen, Kirsten; Moreno, Sonia; Garcia-Roves, Pablo M; Larsen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-16)
      The aim of this study was to find out whether dietary supplementation with Calanus oil (a novel marine oil) or infusion of exenatide (an incretin mimetic) could counteract obesity-induced alterations in myocardial metabolism and improve postischemic recovery of left ventricular (LV) function. Female C57bl/6J mice received high-fat diet (HFD, 45% energy from fat) for 12 wk followed by 8-wk feeding ...

    • Impact of obesity-related inflammation on cardiac metabolism and function 

      Larsen, Terje; Jansen, Kirsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-10)
      This review focuses on the role of adipose tissue in obese individuals in the development of metabolic diseases, and their consequences for metabolic and functional derangements in the heart. The general idea is that the expansion of adipocytes during the development of obesity gives rise to unhealthy adipose tissue, characterized by low-grade inflammation and the release of proinflammatory ...